IntroductionMost patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) have an excellent response to chemoradiation, and trials are now investigating de-escalated treatment.However, up to 25% of patients with HPV-positive OPSCC will experience recurrence, and up to 5% will even progress through primary treatment.Currently, there
Functional analysis of an intergenic non-coding sequence within mce1 operon of M.tuberculosis
Abstract Background The mce operons play an important role in the entry of M.tuberculosis into macrophages and non-phagocytic cells.Their non-redundant function as well as complex regulation is implied by the phenotype of mce mutants.Recently, mce1 operon was found to extend over 13 genes, fadD5 (Rv0166) being the first gene of the operon.The prese
Oculomotor deficits in aryl hydrocarbon receptor null mouse.
The Aryl hydrocarbon Receptor or AhR, a ligand-activated transcription factor, is known to mediate the toxic and carcinogenic effects of various environmental pollutants such as 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD).Recent studies in Caenorhabditis elegans and Drosophila melanogaster show that the orthologs of the AhR are expressed exclusively
The effects and safety of anticoagulation or antiplatelet therapy following TIPS in cirrhotic patients with portal hypertension: A meta-analysis
Introduction: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective way to improve portal hypertension, however, the role of anticoagulation or antiplatelet therapy following TIPS remains controversial.We conducted this study to evaluate the efficacy and safety Luggage Accessories of anticoagulation or antiplatelet therapy following
Intelligent Control of SMART Materials for Energy Harvesting and Storage Devices
The investigation of innovative materials and intelligent control systems has been motivated by the desire to provide sustainable energy solutions, with the aim of improving the efficiency and adaptability of energy harvesting and storage devices.This study introduces an innovative methodology to tackle this issue by combining SMART (Self-Monitorin